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No registration. The access to our data base is fast and free, enjoy.. Free Download Secure Download.. Editors' Rating: 4, Ozkula, C. Uang, and J. Journal of Structural Engineering. Published April 29, DOI: The team of computer scientists and electrical engineers from the University of California San Diego presented their work at the ACML conference, which took place online recently. In addition to personal assistants for smartphones, homes and cars, the method could help improve voice-overs in animated movies, automatic translation of speech in multiple languages—and more.

The method could also help create personalized speech interfaces that empower individuals who have lost the ability to speak, similar to the computerized voice that Stephen Hawking used to communicate, but far more expressive.

Existing methods fall short of this work in two ways. Some systems can synthesize expressive speech for a specific speaker by using several hours of training data for that speaker. Others can synthesize speech from only a few minutes of speech data from a speaker never encountered before; but they are not able to generate expressive speech and only translate text to speech. By contrast, method developed by the UC San Diego team is the only one that can generate with minimal training expressive speech for a subject that has not been part of its training set.

The researchers flagged the pitch and rhythm of the speech in training samples, as a proxy for emotion. This allowed their cloning system to generate expressive speech with minimal training, even for voices it had never encountered before.

Their method can learn speech directly from text; reconstruct a speech sample from a target speaker; and transfer the pitch and rhythm of speech from a different expressive speaker into cloned speech for the target speaker. The team is aware that their work could be used to make deepfake videos and audio clips more accurate and persuasive.

As a result, they plan to release their code with a watermark that will identify the speech created by their method as cloned. The method itself still needs to be improved. It is biased toward English speakers and struggles with speakers with a strong accent. The expressive voice cloning modelk the researchers used. January 3, Microbes are everywhere — in our guts, on our skin, permeating the environments around us. Studying these microbial communities has delivered tremendous insights into disease and good health, but identifying all the distinct species in a sample can be challenging.

Now, a study by an international research team has shown that highly accurate, long-read genomic sequencing technology HiFi can shine a light on this previously hidden biology. Department of Agriculture, the biotechnology company Pacific Biosciences and labs in Russia, Israel and the Netherlands have shown that HiFi, combined with advanced algorithms, can differentiate between nearly identical organisms, allowing researchers to more completely catalogue microbial communities.

The study was published in Nature Biotechnology. This is no small thing: Some E. HiFi recently helped sequence a complete human genome , a feat that had evaded scientists since the Human Genome Project produced an incomplete version 20 years ago.

This paper builds on those findings, showing that long-reads can shine a light on previously invisible organisms. Short-reads, the most common genomic sequencing technique, analyze brief DNA fragments to base pairs and have trouble assembling complete genomes and differentiating between genomically-similar microbes. Long-read technologies, such as HiFi, generate much larger DNA fragments greater than 15, base pairs and have emerged as a potential solution.

As long-read accuracy has increased, the technology has revealed hidden genomic features in amazing detail. In this case, HiFi easily differentiated microbes with only minor genomic variations. In this study, the research team used HiFi long-reads to sequence the microbial metagenome in sheep guts. Their goal was to create complete reference genomes for unique microbial species metagenome-assembled genomes or MAGs. They found HiFi and associated algorithms identified the genomes from species with greater than 90 percent completeness.

Many of these had been invisible to short-read technologies. The applications for this work are quite broad, as the ability to precisely delineate specific microbial species in complex samples could inform many scientific endeavors. Microbes may also help diagnose cancer, decipher red tides, study plastic biodegradation in the ocean and measure carbon release and capture.

Medema, Wageningen University. The device directly measures the movement and speed of electrical signals traveling within a single heart cell—a first—as well as between multiple heart cells. It is also the first to measure these signals inside the cells of 3D tissues. The device, published Dec. If the signal cannot propagate correctly from one part of the heart to another, then some part of the heart cannot receive the signal so it cannot contract. The device consists of a 3D array of microscopic field effect transistors, or FETs, that are shaped like sharp pointed tips.

These tiny FETs pierce through cell membranes without damaging them and are sensitive enough to detect electrical signals—even very weak ones—directly inside the cells. To evade being seen as a foreign substance and remain inside the cells for long periods of time, the FETs are coated in a phospholipid bilayer. The FETs can monitor signals from multiple cells at the same time.

They can even monitor signals at two different sites inside the same cell. This detailed information about signal transportation within a single cell has so far been unknown. To build the device, the team first fabricated the FETs as 2D shapes, and then bonded select spots of these shapes onto a pre-stretched elastomer sheet.

The researchers then loosened the elastomer sheet, causing the device to buckle and the FETs to fold into a 3D structure so that they can penetrate inside cells. The team tested the device on heart muscle cell cultures and on cardiac tissues that were engineered in the lab. The experiments involved placing either the cell culture or tissue on top of the device and then monitoring the electrical signals that the FET sensors picked up.

By seeing which sensors detected a signal first and then measuring the times it took for other sensors to detect the signal, the team could determine which way the signal traveled and its speed. The researchers were able to do this for signals traveling between neighboring cells, and for the first time, for signals traveling within a single heart muscle cell. What makes this even more exciting, said Xu, is that this is the first time that scientists have been able to measure intracellular signals in 3D tissue constructs.

Studying these kinds of details could reveal insights on heart abnormalities at the cellular level, said Gu. Biologists could also use this device to study signal transportation between different organelles in a cell, added Gu.

A device like this could also be used for testing new drugs and seeing how they affect heart cells and tissues. The device would also be useful for studying electrical activity inside neurons. This is a direction that the team is looking to explore next. Down the line, the researchers plan to use their device to record electrical activity in real biological tissue in vivo. Xu envisions an implantable device that can be placed on the surface of a beating heart or on the surface of the cortex.

But the device is still far from that stage. To get there, the researchers have more work to do including fine-tuning the layout of the FET sensors, optimizing the FET array size and materials, and integrating AI-assisted signal processing algorithms into the device.

The interactive 3D excavation site, included last week in an article with Scientific Reports Nature , is being used by an international team to learn more about burial practices, gender-based status and other social behaviors of ancient hunter-gatherer groups. Archaeologists discovered the burial site in during an ongoing excavation at Arma Veirana , a cave in modern-day Italy.

Buried with her were more than 60 pierced shell beads, four pendants and an eagle-owl talon. Prior to advances in 3D scanning technology, archaeologists would have had to go to lengths to document an intact excavation site, including removing entire blocks of substrate for closer study. This gives answers to the archaeological significance which would otherwise have been forever lost during the excavation process.

Over three field seasons, the team collected data and 3D imagery of both the surrounding landscape and burial site using drones and precise laser measurements. Well-documented burials from the time period are extremely rare.

In the future, scientists may be able to glean more knowledge from the Arma Veirana burial using virtual reality environments at UC San Diego. High-definition facilities like the WAVE, an immersive walk-in VR environment, enable researchers to effectively travel directly to the site as it was, and walk again through the excavation from its start to its current state.

Such collaborations are part of a larger effort at QI to advance fields like archaeology with new and emerging technologies. Although these columns comply with modern design standards, our understanding of how they would perform during an earthquake has been limited by a lack of full-scale testing — until now.

Using an earthquake-simulating device called a shake table, researchers at the National Institute of Standards and Technology NIST and the University of California San Diego identified deficiencies in the performance of these columns, with many buckling prematurely. In a paper published in the Journal of Structural Engineering , the researchers propose new limits for column slenderness as a way to reduce the likelihood of column failure during an earthquake. The researchers fastened 48 steel columns of varying dimensions into a hydraulic system called the Seismic Response Modification Device SRMD , which thrusted one end of each column back and forth, replicating the shaking motions of an earthquake.

You can view the experiments in this playlist. But a shaking ground can introduce additional forces in all directions, potentially causing columns to deflect laterally, contributing to story drift. But since then, building designers have satisfied drift requirements by selecting columns with longer, or deeper, and typically more slender webs to boost their lateral stiffness.

These deep columns were OK to use as long as their web dimensions did not surpass certain depth-to-width ratios — known as a slenderness limit — meant to reduce the risk of columns losing their capability to carry weight during earthquakes, Harris said. When the slenderness limits were developed decades ago, engineers did not have the facilities to test the seismic performance of full-scale columns like those actually used in buildings.

To assess the slenderness limits, Harris worked with fellow structural engineering experts at UC San Diego, with access to a shake table designed to put full-scale structural components through the seismic wringer. The machine recreated the effects of earthquakes on columns by applying compressive forces to simulate the weight of the buildings and thrusting one end of the column back and forth with a hydraulic system, representing the lateral loads produced by a quake.

Because the effects of earthquakes can vary so greatly, the researchers used an assortment of loading protocols, which jolted and pressed on the columns in different ways. For certain columns, they applied a steady amount of compression, while varying compression that simulated the overturning effect of the building during an earthquake was used for other columns.

The test specimens were also subjected to earthquake-induced lateral movements to simulate columns of steel buildings that were located either near or far away from the fault line.

They coated the column ends in a layer of white paint that would begin to chip off as the steel bent, making permanent deformation more visually apparent. The researchers recently brought the revised limits before the American Institute of Steel Construction, a standards organization, for review.

If adopted, the more stringent limits on steel column webs could soften the blow of earthquakes, potentially saving newly designed buildings from unnecessary damage or partial collapse. The new limits could be incorporated into standards for evaluating existing buildings as well, enabling engineers to identify deep columns in need of corrective actions such as the addition of bracing. Published Oct.

XX, December 20, From research into new ways to detect and preventCOVID, to new treatments for heart conditions and technology to combat natural disasters and climate change, it has been a busy year at the UC San Diego Jacobs School of Engineering.

Here is a snapshot of research that made headlines this year, thanks to the dedicated work of our faculty, graduate and undergraduate student researchers, research and administrative staff, and campus and community partners. Delve deeper in press coverage in on our press coverage page. The project is aimed at providing simple, affordable and reliable surveillance for COVID infections that can be done daily and easily implemented in resource-poor settings.

Rapid COVID tests are on the rise to deliver results faster to more people, and scientists need an easy, foolproof way to know that these tests work correctly and the results can be trusted. Nanoparticles that pass detection as the novel coronavirus could be just the ticket. Their key ingredients? Viruses from plants or bacteria. If they prove to be safe and effective in people, the vaccines could be a big game changer for global distribution efforts, including those in rural areas or resource-poor communities.

See news coverage in Fast Company. A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. By temporarily repressing a gene involved in sensing pain, the treatment increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness — and without permanently altering the genome. Bioengineers and physicians developed a bio-inspired hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery.

The team tested the hydrogel in rodents and conducted a pilot study on porcine hearts, with promising results. The work was covered in New Atlas and other outlets. UC San Diego engineers developed a soft, stretchy ultrasound patch that can be worn on the skin to monitor blood flow through vessels deep inside the body. Such a device can make it easier to detect cardiovascular problems, like blockages in the arteries that could lead to strokes or heart attacks.

See news coverage in Physics World and Yahoo! How do different parts of the brain communicate with each other during learning and memory formation? A study by researchers at UC San Diego takes a first step at answering this fundamental neuroscience question, thanks to a neural implant that monitors multiple brain regions at the same time.

As California reacts to a record-breaking fire season, a backcountry observation network has reached a milestone of installing more than cameras across the state. The network has become a vital firefighting tool helping first responders confirm and monitor wildfires from ignition through containment. When the work is complete, the table will go from one dimension to three—or from one degree of freedom to three.

The upgraded facility will be better able to replicate complex earthquake motions and will reopen in summer by putting to the test a full-scale, story timber building. The upgrade work has been covered by the American Society of Civil Engineers , among others. Research into solid-state, silicon-based batteries took a significant step with a paper led by nanoengineering professor Shirley Meng, in collaboration with LG Energy Solutions, and published in Science.

The work was broadly covered, including in Business Korea, Engadget and Yahoo! Deian Stefan and his research group have been hard at work making web browsers safer. A tool they designed in collaboration with Mozilla and UT Austin is now part of the latest version of Firefox.

The story received broad coverage, including in The Verge and Engadget. A new technology developed by electrical engineers at UC San Dieg o might one day allow more people to have access to 5G connectivity that provides ultra-fast download speeds along with widespread, reliable coverage —all at the same time. See news coverage in Hackster and Interesting Engineering.

Roboticists led by computer science professor Laurel Riek built a navigation system that will allow robots to better negotiate busy clinical environments in general and emergency departments more specifically. The researchers have also developed a dataset of open source videos to help train robotic navigation systems in the future. The work was featured in PC Mag and United. The robot was quite popular with media outlets as well as YouTubers, including the Veritasium YouTube channel, which has 11 million subscribers.

The video has more than 3. A new wearable device turns the sweat and press of a fingertip into a source of power for small electronics and sensors. This sweat-fueled device is the first to generate power even while the wearer is asleep—no exercise or movement required.

The study is an early step toward building vocal prostheses for humans who have lost the ability to speak. How do pelicans manage to glide above the waves? And why? Researchers in the Department of Mechanical and Aerospace Engineering and the Scripps Institution of Oceanography found an answer by modeling how the birds, the wind and the ocean interact. December 20, Paul A. During his 65 years of research in the field of aerodynamics, Libby made foundational contributions to the fields of supersonic and hypersonic flight, with important applications that include improved heat protection of re-entry vehicles through ablative shielding.

He collaborated in the fields of fluid mechanics and combustion with an impressive array of prominent scientists in the United States and abroad. He also served as the U. Libby produced more than journal publications and authored a monograph on turbulence, publishing his last paper in with his longtime collaborators Professors Michel Champion of the University of Poitiers, France, and K. Bray of the University of Cambridge. This collaboration led, among other things, to the highly cited Bray-Champion-Libby model of turbulent combustion.

In addition, the Homann-Libby flow is named after Libby for his work on the axisymmetric stagnation point flows. These contributions aid in the development of improved aircraft and missile propulsion engines as well as ground-based industrial and transportation processes. Libby received a Guggenheim Fellowship in and a Royal Society Guest Fellowship in , both to support extended stays at the Imperial College of London as a visiting researcher.

He taught graduate and undergraduate engineering classes and served on numerous academic committees, including the UC San Diego Design Review Board. Throughout his career, Libby also enjoyed mentoring graduate students and became lifelong friends with many of them. Libby was born on Sept. Libby also worked as an apprentice engineer with Chance Vought Aircraft and served as an officer in the Navy Bureau of Aeronautics.

In the s, Libby was appointed to the faculty of the Polytechnic Institute of Brooklyn, where he became a tenured professor, collaborating with Professor Antonio Ferri on the development of experimental supersonic and hypersonic research facilities.

Outside of his academic pursuits, Libby was an avid tennis player, retiring from tennis only in his eighties, and an excellent cook. He was a lifelong enthusiast of gardening, classical music, modern architecture, history, and politics.

Libby was preceded in death by his wife Petrina, and is survived by his son John Libby, daughter Patricia Libby Thvedt, and numerous grand-children. Paul A. Libby and Petrina M. December 16, As we prepare to hit the ground running in , we're looking back at all that our students, staff, faculty and partners accomplished last year toward our mission to leverage engineering and computer science for the public good.

Here are a few of our UC San Diego Jacobs School of Engineering highlights from , including launching new programs and research centers, welcoming new faculty, and preparing our new building. Check out our research highlights here. This 9 ranking is up from 11 two years ago, 12 three years ago, 13 four years ago, and 17 five years ago.

It's wonderful to be recognized for some of the ways we are strengthening and growing as a school and as a community. Franklin Antonio Hall nears completion : Franklin Antonio Hall is expected to be open and operational in the spring of The facility will serve as a model for how to build innovation ecosystems with physical roots and virtual infrastructure that extend opportunities well beyond the walls of the building.

The diverse yet complementary research teams in the ,SF building will develop platform technologies that can be pivoted from one application to another to rapidly respond to the needs of the country. Jacobs School Dean Albert P. Pisano shares his vision for Franklin Antonio Hall in this video. New Faculty : The Jacobs School hired 27 new faculty in the past two years. These professors are among the nearly faculty who have joined the UC San Diego Jacobs School of Engineering in the last eight years.

Highly Cited researchers : UC San Diego is home to the 9th largest number of highly cited researchers in the world. The Jacobs School is proud of the 10 engineers and computer scientists who were named among the world's most influential researchers in their fields according to the Clarivate listing of Most Highly Cited Researchers in the World. NextProf Pathfinder : In an effort to diversify the ranks of engineering faculty, the Jacobs School partnered with the University of Michigan to strengthen the NextProf Pathfinder program.

The two-day program is aimed at first and second-year PhD students, as well as students in masters programs, in an effort to keep them pursuing careers in academia. The two schools will partner on the NextProf Pathfinder program going forward, with the institutions swapping hosting duties each year; UC San Diego will host the workshop in The program aims to provide a job upon graduation at one of the Veteran Forge partner organizations to qualifying student veterans at the Jacobs School, while at the same time offering partner organizations access to top talent that is qualified for required security clearances.

UC San Diego is helping drive these innovations as a new member of an industry-university partnership called the Power Management Integration Center. Directed by Dartmouth College, PMIC is innovating power electronics that support higher efficiency, smaller size and reduced cost. And engineered with passion since Permanent Redirect. We use cookies to improve your browsing experience.

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